Publications from the group
| Slow Dynamics Orchestrate Communication Between Binding Sites in the Condensation Domain of a Non-ribosomal Peptide Synthetase | Journal of Molecular Biology |
| NMR chemical shift assignment of the IMLV methyl groups of a di-domain of the Tomaymycin non-ribosomal peptide synthetase | Biomolecular NMR Assignments |
| Long-range conformational changes in the nucleotide-bound states of the DEAD-box helicase Vasa | Biophysical Journal |
| The specificity of intermodular recognition in a prototypical nonribosomal peptide synthetase depends on an adaptor domain | Science Advances |
| Phosphopeptide binding to the N-SH2 domain of tyrosine phosphatase SHP2 correlates with the unzipping of its central Ī²-sheet | Computational and Structural Biology Journal |
| Methods for Structure Determination of SH2 DomaināPhosphopeptide Complexes by NMR | Methods in Molecular Biology |
| NMR Methods to Study the Dynamics of SH2 DomaināPhosphopeptide Complexes | Methods in Molecular Biology |
| An NMR Study of a 300-kDa AAA+ Unfoldase | Journal of Molecular Biology |
| Experiment-guided molecular simulations define a heterogeneous structural ensemble for the PTPN11 tandem SH2 domains | Chemical Science |
| A real-time analysis of GFP unfolding by the AAA+ unfoldase PAN | Journal of Magnetic Resonance |
| The EJC disassembly factor PYM is an intrinsically disordered protein and forms a fuzzy complex with RNA | Frontiers in Molecular Biosciences |
| Structural insights into the activity regulation of full-length non-structural protein 1 from SARS-CoV-2 | Structure |
| Nucleic acidāprotein interfaces studied by MAS solid-state NMR spectroscopy | Journal of Structural Biology: X |
| Structural and functional roles of 2ā²-O-ribose methylations and their enzymatic machinery across multiple classes of RNAs | Current Opinion in Structural Biology |
| 1H, 13C, 15N chemical shift assignments of SHP2 SH2 domains in complex with PD-1 immune-tyrosine motifs | Biomolecular NMR Assignments |
| Observing Protein Degradation by the PAN-20S Proteasome by Time-Resolved Neutron Scattering | Biophysical Journal |
| Specificity and regulation of phosphotyrosine signaling through SH2 domains | Journal of Structural Biology: X |
| Structure of a ProteināRNA Complex by Solid-State NMR Spectroscopy | Angewandte Chemie International Edition |
| The guide sRNA sequence determines the activity level of box C/D RNPs | eLife |
| Small-Angle Neutron Scattering of RNAāProtein Complexes | Methods in Molecular Biology |
| Molecular mechanism of SHP2 activation by PD-1 stimulation | Science Advances |
| Histone chaperone exploits intrinsic disorder to switch acetylation specificity | Nature Communications |
| Solid-state NMR Spectroscopy of RNA | Methods in Enzymology |
| Rapid access to RNA resonances by proton-detected solid-state NMR at >100 kHz MAS | Chemical Communications |
| Isotope labeling for studying RNA by solid-state NMR spectroscopy | Journal of Biomolecular NMR |
| Structural characterization of the Asf1āRtt109 interaction and its role in histone acetylation | Nucleic Acids Research |
| Chemical Analysis of a "Miller-Type" Complex Prebiotic Broth | Origins of Life and Evolution of Biospheres |
| M3: an integrative framework for structure determination of molecular machines | Nature Methods |
| Structure-Based Design of Scaffolds Targeting PDE10A by INPHARMA-NMR | Journal of Chemical Information and Modeling |
| On-the-Fly Integration of Data from a Spin-Diffusion-Based NMR Experiment into ProteināLigand Docking | Journal of Chemical Information and Modeling |
| A Distinct, Sequence-Induced Conformation Is Required for Recognition of the Constitutive Decay Element RNA by Roquin | Structure |
| The structure of the SOLE element of oskar mRNA | RNA |
| Identification of new hit scaffolds by INPHARMA-guided virtual screening | MedChemComm |
| RNA structure determination by solid-state NMR spectroscopy | Nature Communications |
| An integrated approach for genome annotation of the eukaryotic thermophile Chaetomium thermophilum | Nucleic Acids Research |
| Six Subgroups and Extensive Recent Duplications Characterize the Evolution of the Eukaryotic Tubulin Protein Family | Genome Biology and Evolution |
| Molecular Recognition of Epothilones by Microtubules and Tubulin Dimers Revealed by Biochemical and NMR Approaches | ACS Chemical Biology |
| Present and future of NMR for RNAāprotein complexes: A perspective of integrated structural biology | Journal of Magnetic Resonance |
| The structure of the box C/D enzyme reveals regulation of RNA methylation | Nature |
| A Reducing Milieu Renders Cofilin Insensitive to Phosphatidylinositol 4,5-Bisphosphate (PIP2) Inhibition | Journal of Biological Chemistry |
| A Suite of Solid-State NMR Experiments for RNA Intranucleotide Resonance Assignment in a 21 kDa Protein-RNA Complex | Angewandte Chemie International Edition |
| Accounting for Conformational Variability in ProteināLigand Docking with NMR-Guided Rescoring | Journal of the American Chemical Society |
| Structural Principles of RNA Catalysis in a 2ā²ā5ā² Lariat-Forming Ribozyme | Journal of the American Chemical Society |
| Towards Improved Quality of GPCR Models by Usage of Multiple Templates and Profile-Profile Comparison | PLOS ONE |
| ProteināRNA Interfaces Probed by 1H-Detected MAS Solid-State NMR Spectroscopy | Angewandte Chemie International Edition |
| Synthesis and biological evaluation of a water-soluble derivative of the potent V-ATPase inhibitor archazolid | Bioorganic & Medicinal Chemistry Letters |
| Phf19 links methylated Lys36 of histone H3 to regulation of Polycomb activity | Nature Structural and Molecular Biology |
| The description of protein internal motions aids selection of ligand binding poses by the INPHARMA method | Journal of Biomolecular NMR |
| Understanding the Inhibitory Effect of Highly Potent and Selective Archazolides Binding to the Vacuolar ATPase | Journal of Chemical Information and Modeling |
| Hyperpolarized Binding Pocket Nuclear Overhauser Effect for Determination of Competitive Ligand Binding | Angewandte Chemie International Edition |
| NMR in natural products: understanding conformation, configuration and receptor interactions | Natural Product Reports |
| An NMR-based scoring function improves the accuracy of binding pose predictions by docking by two orders of magnitude | Journal of Biomolecular NMR |
| Computational techniques are valuable tools for the discovery of proteināprotein interaction inhibitors: The 14-3-3Ļ case | Bioorganic & Medicinal Chemistry Letters |
| Recognition of 2ā²-O-Methylated 3ā²-End of piRNA by the PAZ Domain of a Piwi Protein | Structure |
| 13C-Detection in RNA Bases:ā Revealing StructureāChemical Shift Relationships | Journal of the American Chemical Society |
| Binding of the Human Prp31 Nop Domain to a Composite RNAāProtein Platform in U4 snRNP | Science |
| High-Resolution Solid-State NMR Structure of an Anticancer Agent | ChemMedChem |
| Structural Basis of the Activity of the Microtubule-Stabilizing Agent Epothiloneā A Studied by NMR Spectroscopy in Solution | Angewandte Chemie International Edition |
| Side-Chain Orientation and Hydrogen-Bonding Imprint Supra-Ļc Motion on the Protein Backbone of Ubiquitin | Angewandte Chemie International Edition |
| The INPHARMA Method: Protein-Mediated Interligand NOEs for Pharmacophore Mapping | Angewandte Chemie International Edition |
| LigandāTarget Interactions: What Can We Learn from NMR? | Annual Review of Biophysics |
| Identification of a Novel Pharmacophore for Peptide Toxins Interacting with K+ Channels | Journal of Biological Chemistry |
| Assignment and NOE Analysis of 2'-Hydroxyl Protons in RNA:ā Implications for Stabilization of RNA A-Form Duplexes | Journal of the American Chemical Society |
| ĪŗM-Conotoxin RIIIK, Structural and Functional Novelty in a K+ Channel Antagonist | Biochemistry |
| Structure of the NCoA-1/SRC-1 PAS-B Domain Bound to the LXXLL Motif of the STAT6 Transactivation Domain | Journal of Molecular Biology |
| A novel PH-CT-COSY methodology for measuring JPH coupling constants in unlabeled nucleic acids. Application to HIV-2 TAR RNA | Journal of Biomolecular NMR |
| Determination of Aliphatic Side-Chain Conformation Using Cross-Correlated Relaxation:ā Application to an Extraordinarily Stable 2ā²-aminoethoxy-Modified Oligonucleotide Triplex | Journal of the American Chemical Society |
| Residual Dipolar Coupling TOCSY for Direct Through Space Correlations of Base Protons and Phosphorus Nuclei in RNA | Journal of the American Chemical Society |
| COIN TACSY, a Novel Approach to Tailored Correlation Spectroscopy | Journal of Magnetic Resonance |
| Cross-Correlated Relaxation for Measurement of Angles between Tensorial Interactions | Methods in Enzymology |
| A new method for the simultaneous measurement of magnitude and sign of 1DCH and 1DHH dipolar couplings in methylene groups | Journal of Biomolecular NMR |
| Errors in the Measurement of Cross-Correlated Relaxation Rates and How to Avoid Them | Journal of Magnetic Resonance |
| Ubiquitin Backbone Motion Studied via NHNāCāCĪ± DipolarāDipolar and CāāCāCĪ±/NHN CSAāDipolar Cross-Correlated Relaxation | Journal of the American Chemical Society |
| TransferredāCross-CorrelatedāRelaxation:āApplication to the Determination of Sugar Pucker in an Aminoacylated tRNA-Mimetic Weakly Bound to EF-Tu | Journal of the American Chemical Society |
| New Methylene Specific Experiments for the Measurement of Scalar SpināSpin Coupling Constants between Protons Attached to 13C | Journal of Magnetic Resonance |
| PLUSH TACSY: Homonuclear planar TACSY with two-band selective shaped pulses applied to CĪ±,Cā² transfer and CĪ²,Caromatic correlations | Journal of Biomolecular NMR |
| Conformational analysis of Dolastatin 10: An NMR and theoretical approach | Biopolymers |