Senior Scientific Officer
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Publications within the group:
Long-range conformational changes in the nucleotide-bound states of the DEAD-box helicase Vasa | Biophysical Journal |
The specificity of intermodular recognition in a prototypical nonribosomal peptide synthetase depends on an adaptor domain | Science Advances |
Phosphopeptide binding to the N-SH2 domain of tyrosine phosphatase SHP2 correlates with the unzipping of its central β-sheet | Computational and Structural Biology Journal |
Methods for Structure Determination of SH2 Domain-Phosphopeptide Complexes by NMR | Methods in Molecular Biology |
NMR Methods to Study the Dynamics of SH2 Domain-Phosphopeptide Complexes | Methods in Molecular Biology |
An NMR Study of a 300-kDa AAA+ Unfoldase | Journal of Molecular Biology |
Experiment-guided molecular simulations define a heterogeneous structural ensemble for the PTPN11 tandem SH2 domains | Chemical Science |
A real-time analysis of GFP unfolding by the AAA+ unfoldase PAN | Journal of Magnetic Resonance |
The EJC disassembly factor PYM is an intrinsically disordered protein and forms a fuzzy complex with RNA | Frontiers in Molecular Biosciences |
Structural insights into the activity regulation of full-length non-structural protein 1 from SARS-CoV-2 | Structure |
Identification of RNA Base Pairs and Complete Assignment of Nucleobase Resonances by Proton-Detected Solid-State NMR Spectroscopy at 100 kHz MAS | Angewandte Chemie International Edition |
1H, 13C, and 15N backbone chemical-shift assignments of SARS-CoV-2 non-structural protein 1 (leader protein) | Biomolecular NMR Assignments |
Large-Scale Recombinant Production of the SARS-CoV-2 Proteome for High-Throughput and Structural Biology Applications | Frontiers in Molecular Biosciences |
Phosphotyrosine couples peptide binding and SHP2 activation via a dynamic allosteric network | Computational and Structural Biology Journal |
1H, 13C, 15N chemical shift assignments of SHP2 SH2 domains in complex with PD-1 immune-tyrosine motifs | Biomolecular NMR Assignments |
The guide sRNA sequence determines the activity level of box C/D RNPs | eLife |
Molecular mechanism of SHP2 activation by PD-1 stimulation | Science Advances |
Histone chaperone exploits intrinsic disorder to switch acetylation specificity | Nature Communications |
Structural characterization of the Asf1–Rtt109 interaction and its role in histone acetylation | Nucleic Acids Research |
Recognition of 2′-O-Methylated 3′-End of piRNA by the PAZ Domain of a Piwi Protein | Structure |
Intermolecular Protein−RNA Interactions Revealed by 2D 31P−15N Magic Angle Spinning Solid-State NMR Spectroscopy | Journal Of The American Chemical Society |