Joined the group
About
I obtained my undergraduate degree in Pharmaceutical Chemistry and Technology from the University of Bari (Italy). For my thesis, I worked in Dr. Anna Hirsh’s lab on the design and synthesis of drug candidates targeting the protein DXS at HIPS in Saarbrücken (Germany). In 2019, I started my PhD in Carlomagno group at the BMWZ in Hannover (Germany), where I have been working on the structural and biophysical characterization of SH2 domains in complex with phosphopeptides, employing NMR spectroscopy and isothermal titration calorimetry (ITC). I moved to Birmingham in April 2022.
Publications within the group:
NMR Methods to Study the Dynamics of SH2 Domain–Phosphopeptide Complexes | Methods in Molecular Biology | 2023 |
Methods for Structure Determination of SH2 Domain–Phosphopeptide Complexes by NMR | Methods in Molecular Biology | 2023 |
Recruitment of phospholipase Cγ1 to the non-structural membrane protein pK15 of Kaposi Sarcoma-associated herpesvirus promotes its Src-dependent phosphorylation | PLOS Pathogens | 2021 |
Phosphotyrosine couples peptide binding and SHP2 activation via a dynamic allosteric network | Computational and Structural Biology Journal | 2021 |