I am an NMR spectroscopist with biotechnological backgrounds. Currently I am working with the structural characterization of RNA binding proteins and the determination of the binding of fragment ligands to proteins of pharmaceutical interest, such as Kinases and Phosphodiestherases and GPCR.


• Nuclear magnetic resonance NMR
• Expression of recombinant proteins in bacterial systems (E.coli) 
• Protein purification using FPLC chromatographers 
• Molecular biology 
• quantitative assays
• Molecular Modelling, Molecular dynamics
• Extensive knowledge of Python and scientific python libraries (numpy, scipy, matplotlib)



Codutti L, Grimaldi M, Carlomagno T

Structure-Based Design of Scaffolds Targeting PDE10A by INPHARMA-NMR.

J Chem Inf Model. 2017 Jun 26;57(6):1488-1498. doi: link


Scherer S, Wollrab E, Codutti L, Carlomagno T, da Costa SG, Volkmer A, Bronja A, Schmitz OJ, Ott A

Chemical Analysis of a "Miller-Type" Complex Prebiotic Broth : Part II: Gas, Oil, Water and the Oil/Water-Interface.

Orig Life Evol Biosph. 2017 Dec;47(4):381-403. doi: link


Coci EG, Codutti L, Fink C, Bartsch S, Gruning G, Lucke T, Kurth I, Riedel J

Novel homozygous missense mutation in ALDH7A1 causes neonatal pyridoxine dependent epilepsy.

Mol Cell Probes. 2017 Apr;32:18-23. doi: link


Kuhne C, Singer HM, Grabisch E, Codutti L, Carlomagno T, Scrima A, Erhardt M

RflM mediates target specificity of the RcsCDB phosphorelay system for transcriptional repression of flagellar synthesis in Salmonella enterica.

Mol Microbiol. 2016 Sep;101(5):841-55. doi: link


Wollrab E, Scherer S, Aubriet F, Carre V, Carlomagno T, Codutti L, Ott A

Chemical Analysis of a "Miller-Type" Complex Prebiotic Broth: Part I: Chemical Diversity, Oxygen and Nitrogen Based Polymers.

Orig Life Evol Biosph. 2016 Jun;46(2-3):149-69. doi: link


Onila I, ten Brink T, Fredriksson K, Codutti L, Mazur A, Griesinger C, Carlomagno T, Exner TE

On-the-Fly Integration of Data from a Spin-Diffusion-Based NMR Experiment into Protein-Ligand Docking.

J Chem Inf Model. 2015 Sep 28;55(9):1962-72. doi: link


Codutti L, Leppek K, Zalesak J, Windeisen V, Masiewicz P, Stoecklin G, Carlomagno T

A Distinct, Sequence-Induced Conformation Is Required for Recognition of the Constitutive Decay Element RNA by Roquin.

Structure. 2015 Aug 4;23(8):1437-1447. doi: link


Skjaerven L, Codutti L, Angelini A, Grimaldi M, Latek D, Monecke P, Dreyer MK, Carlomagno T

Accounting for conformational variability in protein-ligand docking with NMR-guided rescoring.

J Am Chem Soc. 2013 Apr 17;135(15):5819-27. doi: link


Carlomagno T, Amata I, Codutti L, Falb M, Fohrer J, Masiewicz P, Simon B

Structural principles of RNA catalysis in a 2'-5' lariat-forming ribozyme.

J Am Chem Soc. 2013 Mar 20;135(11):4403-11. doi: link


Rennella E, Corazza A, Codutti L, Causero A, Bellotti V, Stoppini M, Viglino P, Fogolari F, Esposito G

Single-shot NMR measurement of protein unfolding landscapes.

Biochim Biophys Acta. 2012 Jun;1824(6):842-9. doi: link


Rennella E, Corazza A, Codutti L, Bellotti V, Stoppini M, Viglino P, Fogolari F, Esposito G

Determining the energy landscape of proteins by a fast isotope exchange NMR approach.

J Am Chem Soc. 2012 Mar 14;134(10):4457-60. doi: link


Fogolari F, Corazza A, Varini N, Rotter M, Gumral D, Codutti L, Rennella E, Viglino P, Bellotti V, Esposito G

Molecular dynamics simulation of beta(2)-microglobulin in denaturing and stabilizing conditions.

Proteins. 2011 Mar;79(3):986-1001. doi: link


Giorgetti S, Raimondi S, Pagano K, Relini A, Bucciantini M, Corazza A, Fogolari F, Codutti L, Salmona M, Mangione P, Colombo L, De Luigi A, Porcari R, Gliozzi A, Stefani M, Esposito G, Bellotti V, Stoppini M

Effect of tetracyclines on the dynamics of formation and destructuration of beta2-microglobulin amyloid fibrils.

J Biol Chem. 2011 Jan 21;286(3):2121-31. doi: link


Codutti L, Picotti P, Marin O, Dewilde S, Fogolari F, Corazza A, Viglino P, Moens L, Esposito G, Fontana A

Conformational stability of neuroglobin helix F--possible effects on the folding pathway within the globin family.

FEBS J. 2009 Sep;276(18):5177-90. doi: link


Codutti L, van Ingen H, Vascotto C, Fogolari F, Corazza A, Tell G, Quadrifoglio F, Viglino P, Boelens R, Esposito G

The solution structure of DNA-free Pax-8 paired box domain accounts for redox regulation of transcriptional activity in the pax protein family.

J Biol Chem. 2008 Nov 28;283(48):33321-8. doi: link