Nataliya Danilenko

Summary

I received my undergrad degree in Molecular Biology from Moscow State University. My thesis was done at EIMB RAS under Prof. VL Karpov supervision and was related to yeast transcriptional factors. I started my PhD in Prof. Carlomagno group in 09/2014 and currently I am working on a structural model of a large protein complex involved in histone modifications and nucleosome assembly. The main methods I employ are NMR, small-angle solution scattering and computational modelling (namely, HADDOCK).

 

2017

Integrative structure biology

 

The most important technique for structural biology in solution is Nuclear Magnetic Resonance Spectroscopy (NMR). However, the standard NMR methodology reaches its limit when applied to high-molecular-weight complexes, where the large line-width of NMR resonances impedes an accurate structure determination. It is common sense that NMR “does not work” for molecules >50 kDa.

Teresa Carlomagno

Professor of Structural Chemistry at the Leibniz University Hannover

Associated group leader in NMR-Based Structural Chemistry at the Helmoltz Institute for Infection Research (Braunschweig)

Visiting group leader at the European Molecular Biology Laboratory (Heidelberg)