Neha is currently working to elucidate the role of tudor domains involved in piRNA biogenesis
Application and preparation of Cell free transcription/translation systems and in vitro transcription. Preparation and Structural analysis of macromolecular protein-RNA complexes including Ribosome and Ribosome Nascent Chain complexes by various biophysical techniques.
Schedlbauer A, Kaminishi T, Ochoa-Lizarralde B, Dhimole N, Zhou S, Lopez-Alonso JP, Connell SR, Fucini P
Structural characterization of an alternative mode of tigecycline binding to the bacterial ribosome.
Antimicrob Agents Chemother. 2015 May;59(5):2849-54. doi: link
Gelis I, Vitzthum V, Dhimole N, Caporini MA, Schedlbauer A, Carnevale D, Connell SR, Fucini P, Bodenhausen G
Solid-state NMR enhanced by dynamic nuclear polarization as a novel tool for ribosome structural biology.
J Biomol NMR. 2013 Jun;56(2):85-93. doi: link
Tomar SK, Dhimole N, Chatterjee M, Prakash B
Distinct GDP/GTP bound states of the tandem G-domains of EngA regulate ribosome binding.
Nucleic Acids Res. 2009 Apr;37(7):2359-70. doi: link
Jain N, Dhimole N, Khan AR, De D, Tomar SK, Sajish M, Dutta D, Parrack P, Prakash B
E. coli HflX interacts with 50S ribosomal subunits in presence of nucleotides.
Biochem Biophys Res Commun. 2009 Feb 6;379(2):201-5. doi: link