1. Ph.D. positions in NMR spectroscopy of molecular machines
We are looking for Ph.D. candidates to study:
- Multicomponent complex involved in protein quality control and homeostasis.
- RNP complexes involved in the piRNA pathway
- RNP complexes involved in bacterial infections
Structural and mechanistic studies will follow an integrative structural biology approach, as outlined in the description of our research activities.
Qualifications and Experience
The successful candidate will have a master degree in Chemistry, Biochemistry, Molecular Biology or a related topic. Excellent laboratory skills, experience with NMR spectroscopy and protein expression and purification will be considered as a bonus. Scientific curiosity, analytical skills, broad scientific interests and an excellent university track record are essential. In addition, good communication skills along with the ability to interact with other scientists in an international environment are required.
As an equal opportunities employer, Leibniz Universität Hannover intends to promote women in the context of statutory requirements and encourages applications from qualified female scientists. Equally qualified applicants with disabilities will be given preferential treatment.
To apply, please email a cover letter, CV (in English) and contact information of three references to:
Prof. Dr. Teresa Carlomagno
E.mail: teresa.carlomagno %at% oci.uni-hannover.de
2. Ph.D. Position available
A PhD position is available in the field of solid-state NMR characterization of RNA in protein-RNA complexes.
Research Assistant (phD candidate)
(Salary Scale 13 TV-L)
The position is limited to 3 years. The extent of the position is equivalent to 50% of the standard working time.
Responsibilities and duties
The junior solid-state NMR research group of Alexander Marchanka focuses on the development of solid-state NMR techniques for structural studies of RNA in large biomolecular complexes. Moreover, in close collaboration with the solution-state NMR group of Prof. Teresa Carlomagno we are working on the characterization of ribonucleoprotein complexes in viral systems by a plethora of modern magnetic resonance techniques (NMR and EPR).
The successful candidate will work on an interdisciplinary research project combining activities both in the wet lab (organic synthesis, protein expression and purification, RNA synthesis) and in solid-state NMR and EPR spectroscopy.
The candidate should hold a master degree and be highly motivated with a strong interest in (bio)chemistry and biophysics. Previous experience in organic synthesis and/or biochemistry of proteins and RNA is required. Experience in the field of magnetic resonance spectroscopy is of advantage.
The new established Center of Biomolecular Drug Research (BMWZ) at the University of Hannover offers an exciting and stimulating research environment. State-of-the art instrumentation includes high-field solution and solid-state NMR spectrometers operating at 850 MHz and 600 MHz. Access to ultra high-field NMR spectrometers is granted by collaborative research grants. Fully established protein- and RNA purification laboratories and a high performance computation cluster are available.
As an equal opportunities employer, Leibniz Universität Hannover intends to promote women in the context of statutory requirements. For this reason suitably qualified women are specifically invited to apply.
Equally qualified applicants with disabilities will be given preferential treatment.
Please send your application with the usual documents and papers to
Gottfried Wilhelm Leibniz Universität Hannover
Zentrum für Biomolekulare Wirkstoffe (BMWZ)
Dr. Alexander Marchanka
Schneiderberg 38, 30167 Hannover
E-Mail: alexander.marchanka at oci.uni-hannover.de
For further information, please contact Alexander Marchanka, e-mail, who will be pleased to assist.